TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons
TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons
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Ann Arbor: American Society for Clinical Investigation
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English
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Ann Arbor: American Society for Clinical Investigation
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The TET family of dioxygenases promote DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Hypothalamic agouti-related peptide-expressing (AGRP-expressing) neurons play an essential role in driving feeding, while also modulating nonfeeding behaviors. Besides AGRP, these neurons produce neuropeptide Y (NPY) and the neu...
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TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_6327ef9376aa4b878e87ef53442e9d52
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6327ef9376aa4b878e87ef53442e9d52
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI162365