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TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons

TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6327ef9376aa4b878e87ef53442e9d52

TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons

About this item

Full title

TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons

Publisher

Ann Arbor: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2022-10, Vol.132 (19), p.1-16

Language

English

Formats

Publication information

Publisher

Ann Arbor: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The TET family of dioxygenases promote DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Hypothalamic agouti-related peptide-expressing (AGRP-expressing) neurons play an essential role in driving feeding, while also modulating nonfeeding behaviors. Besides AGRP, these neurons produce neuropeptide Y (NPY) and the neu...

Alternative Titles

Full title

TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6327ef9376aa4b878e87ef53442e9d52

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6327ef9376aa4b878e87ef53442e9d52

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI162365

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