Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer
Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer
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Author / Creator
Wagner, Alex H. , Devarakonda, Siddhartha , Skidmore, Zachary L. , Krysiak, Kilannin , Ramu, Avinash , Trani, Lee , Kunisaki, Jason , Masood, Ashiq , Waqar, Saiama N. , Spies, Nicholas C. , Morgensztern, Daniel , Waligorski, Jason , Ponce, Jennifer , Fulton, Robert S. , Maggi, Leonard B. , Weber, Jason D. , Watson, Mark A. , O’Conor, Christopher J. , Ritter, Jon H. , Olsen, Rachelle R. , Cheng, Haixia , Mukhopadhyay, Anandaroop , Can, Ismail , Cessna, Melissa H. , Oliver, Trudy G. , Mardis, Elaine R. , Wilson, Richard K. , Griffith, Malachi , Griffith, Obi L. and Govindan, Ramaswamy
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Nearly all patients with small cell lung cancer (SCLC) eventually relapse with chemoresistant disease. The molecular mechanisms driving chemoresistance in SCLC remain un-characterized. Here, we describe whole-exome sequencing of paired SCLC tumor samples procured at diagnosis and relapse from 12 patients, and unpaired relapse samples from 18 additi...
Alternative Titles
Full title
Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer
Authors, Artists and Contributors
Author / Creator
Devarakonda, Siddhartha
Skidmore, Zachary L.
Krysiak, Kilannin
Ramu, Avinash
Trani, Lee
Kunisaki, Jason
Masood, Ashiq
Waqar, Saiama N.
Spies, Nicholas C.
Morgensztern, Daniel
Waligorski, Jason
Ponce, Jennifer
Fulton, Robert S.
Maggi, Leonard B.
Weber, Jason D.
Watson, Mark A.
O’Conor, Christopher J.
Ritter, Jon H.
Olsen, Rachelle R.
Cheng, Haixia
Mukhopadhyay, Anandaroop
Can, Ismail
Cessna, Melissa H.
Oliver, Trudy G.
Mardis, Elaine R.
Wilson, Richard K.
Griffith, Malachi
Griffith, Obi L.
Govindan, Ramaswamy
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_633460ab94c74c7ba9529694b90819e7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_633460ab94c74c7ba9529694b90819e7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06162-9
