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T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6334ebee5b454f54b0c32fa67fdc1261

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

About this item

Full title

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-10, Vol.7 (1), p.13257-13257, Article 13257

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

CD1 proteins present microbial lipids to T cells. Germline-encoded mycolyl lipid-reactive (GEM) T cells with conserved αβ T cell receptors (TCRs) recognize CD1b presenting mycobacterial mycolates. As the molecular basis underpinning TCR recognition of CD1b remains unknown, here we determine the structure of a GEM TCR bound to CD1b presenting glucos...

Alternative Titles

Full title

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6334ebee5b454f54b0c32fa67fdc1261

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6334ebee5b454f54b0c32fa67fdc1261

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms13257

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