Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria
Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria
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Full title
Author / Creator
Grinter, Rhys , Ney, Blair , Brammananth, Rajini , Barlow, Christopher K. , Cordero, Paul R. F. , Gillett, David L. , Izoré, Thierry , Cryle, Max J. , Harold, Liam K. , Cook, Gregory M. , Taiaroa, George , Williamson, Deborah A. , Warden, Andrew C. , Oakeshott, John G. , Taylor, Matthew C. , Crellin, Paul K. , Jackson, Colin J. , Schittenhelm, Ralf B. , Coppel, Ross L. and Greening, Chris
Publisher
1752 N St., N.W., Washington, DC: American Society for Microbiology
Journal title
Language
English
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Publisher
1752 N St., N.W., Washington, DC: American Society for Microbiology
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Contents
F420 is a low-potential redox cofactor used by diverse bacteria and archaea. In mycobacteria, this cofactor has multiple roles, including adaptation to redox stress, cell wall biosynthesis, and activation of the clinical antitubercular prodrugs pretomanid and delamanid. A recent biochemical study proposed a revised biosynthesis pathway for F420 in...
Alternative Titles
Full title
Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria
Authors, Artists and Contributors
Author / Creator
Ney, Blair
Brammananth, Rajini
Barlow, Christopher K.
Cordero, Paul R. F.
Gillett, David L.
Izoré, Thierry
Cryle, Max J.
Harold, Liam K.
Cook, Gregory M.
Taiaroa, George
Williamson, Deborah A.
Warden, Andrew C.
Oakeshott, John G.
Taylor, Matthew C.
Crellin, Paul K.
Jackson, Colin J.
Schittenhelm, Ralf B.
Coppel, Ross L.
Greening, Chris
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_63558d0234fb43f688726db29ee00c9a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_63558d0234fb43f688726db29ee00c9a
Other Identifiers
ISSN
2379-5077
E-ISSN
2379-5077
DOI
10.1128/mSystems.00389-20
