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SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation...

SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_636b189fddc14c0eaedf12314fffd4e1

SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels

About this item

Full title

SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels

Publisher

London: BioMed Central

Journal title

Genome Biology, 2021-03, Vol.22 (1), p.1-82, Article 82

Language

English

Formats

Publication information

Publisher

London: BioMed Central

More information

Scope and Contents

Contents

Background Alternative polyadenylation (APA) refers to the regulated selection of polyadenylation sites (PASs) in transcripts, which determines the length of their 3′ untranslated regions (3′UTRs). We have recently shown that SRSF3 and SRSF7, two closely related SR proteins, connect APA with mRNA export. The mechanism underlying APA regulation by S...

Alternative Titles

Full title

SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_636b189fddc14c0eaedf12314fffd4e1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_636b189fddc14c0eaedf12314fffd4e1

Other Identifiers

ISSN

1474-760X,1474-7596

E-ISSN

1474-760X

DOI

10.1186/s13059-021-02298-y

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