Sonic Hedgehog switches on Wnt/planar cell polarity signaling in commissural axon growth cones by re...
Sonic Hedgehog switches on Wnt/planar cell polarity signaling in commissural axon growth cones by reducing levels of Shisa2
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Commissural axons switch on responsiveness to Wnt attraction during midline crossing and turn anteriorly only after exiting the floor plate. We report here that Sonic Hedgehog (Shh)-Smoothened signaling downregulates Shisa2, which inhibits the glycosylation and cell surface presentation of Frizzled3 in rodent commissural axon growth cones. Constitu...
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Sonic Hedgehog switches on Wnt/planar cell polarity signaling in commissural axon growth cones by reducing levels of Shisa2
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TN_cdi_doaj_primary_oai_doaj_org_article_63920654b70e42e8859ad534287c5239
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_63920654b70e42e8859ad534287c5239
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.25269
