Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mut...
Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load
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Author / Creator
Reijm, Sanne , Kissel, Theresa , Stoeken-Rijsbergen, Gerrie , Slot, Linda M. , Wortel, Corrie M. , van Dooren, Hugo J. , Levarht, Nivine E. W. , Kampstra, Arieke S. B. , Derksen, Veerle F. A. M. , Heer, Pleuni Ooijevaar-de , Bang, Holger , Drijfhout, Jan W. , Trouw, Leendert A. , Huizinga, Tom W. J. , Rispens, Theo , Scherer, Hans U. and Toes, René E. M.
Publisher
London: BioMed Central Ltd
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Language
English
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Publisher
London: BioMed Central Ltd
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Contents
Background Anti-modified protein antibodies (AMPA) targeting citrullinated, acetylated and/or carbamylated self-antigens are hallmarks of rheumatoid arthritis (RA). Although AMPA-IgG cross-reactivity to multiple post-translational modifications (PTMs) is evident, it is unknown whether the first responding B cells, expressing IgM, display similar ch...
Alternative Titles
Full title
Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load
Authors, Artists and Contributors
Author / Creator
Kissel, Theresa
Stoeken-Rijsbergen, Gerrie
Slot, Linda M.
Wortel, Corrie M.
van Dooren, Hugo J.
Levarht, Nivine E. W.
Kampstra, Arieke S. B.
Derksen, Veerle F. A. M.
Heer, Pleuni Ooijevaar-de
Bang, Holger
Drijfhout, Jan W.
Trouw, Leendert A.
Huizinga, Tom W. J.
Rispens, Theo
Scherer, Hans U.
Toes, René E. M.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_63a2b8cb09d24e27bf69a399f673442e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_63a2b8cb09d24e27bf69a399f673442e
Other Identifiers
ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-021-02609-5