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Understanding the key features of the spontaneous formation of bona fide prions through a novel meth...

Understanding the key features of the spontaneous formation of bona fide prions through a novel meth...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_63c13fcaea6249e3a04b3b8cea76b3ad

Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation

About this item

Full title

Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation

Publisher

England: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2023-09, Vol.11 (1), p.145-30, Article 145

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Among transmissible spongiform encephalopathies or prion diseases affecting humans, sporadic forms such as sporadic Creutzfeldt–Jakob disease are the vast majority. Unlike genetic or acquired forms of the disease, these idiopathic forms occur seemingly due to a random event of spontaneous misfolding of the cellular PrP (PrP
C
) into the patho...

Alternative Titles

Full title

Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_63c13fcaea6249e3a04b3b8cea76b3ad

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_63c13fcaea6249e3a04b3b8cea76b3ad

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-023-01640-8

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