Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic color...
Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer
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Author / Creator
Arai, Hiroyuki , Xiao, Yi , Loupakis, Fotios , Kawanishi, Natsuko , Wang, Jingyuan , Battaglin, Francesca , Soni, Shivani , Zhang, Wu , Mancao, Christoph , Salhia, Bodour , Mumenthaler, Shannon M , Weisenberger, Daniel J , Liang, Gangning , Cremolini, Chiara , Falcone, Alfredo , Millstein, Joshua and Lenz, Heinz-Josef
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publisher
England: BMJ Publishing Group Ltd
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Contents
BackgroundImmunogenic cell death (ICD) is a tumor cell death involving both innate and adaptive immune responses. Given published findings that oxaliplatin, but not irinotecan, drives ICD, we investigated whether single nucleotide polymorphisms (SNPs) in the ICD pathway are associated with the efficacy of oxaliplatin-based chemotherapy in metastati...
Alternative Titles
Full title
Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_63cb3449cb6048b68ddf421f2efdf186
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_63cb3449cb6048b68ddf421f2efdf186
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-001714
