Multimerization through Pegylation Improves Pharmacokinetic Properties of scFv Fragments of GD2-Spec...
Multimerization through Pegylation Improves Pharmacokinetic Properties of scFv Fragments of GD2-Specific Antibodies
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Antigen-binding fragments of antibodies specific to the tumor-associated ganglioside GD2 are well poised to play a substantial role in modern GD2-targeted cancer therapies, however, rapid elimination from the body and reduced affinity compared to full-length antibodies limit their therapeutic potential. In this study, scFv fragments of GD2-specific...
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Full title
Multimerization through Pegylation Improves Pharmacokinetic Properties of scFv Fragments of GD2-Specific Antibodies
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TN_cdi_doaj_primary_oai_doaj_org_article_63d260e83a8b4c54842c491d2f1b4b63
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_63d260e83a8b4c54842c491d2f1b4b63
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules24213835
