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Exploring the principles behind antibiotics with limited resistance

Exploring the principles behind antibiotics with limited resistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_64049a82bac7484096090352369a474e

Exploring the principles behind antibiotics with limited resistance

About this item

Full title

Exploring the principles behind antibiotics with limited resistance

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-02, Vol.16 (1), p.1842-18, Article 1842

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Antibiotics that target multiple cellular functions are anticipated to be less prone to bacterial resistance. Here we hypothesize that while dual targeting is crucial, it is not sufficient in preventing resistance. Only those antibiotics that simultaneously target membrane integrity and block another cellular pathway display reduced resistance deve...

Alternative Titles

Full title

Exploring the principles behind antibiotics with limited resistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_64049a82bac7484096090352369a474e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_64049a82bac7484096090352369a474e

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-025-56934-3

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