Exploring the principles behind antibiotics with limited resistance
Exploring the principles behind antibiotics with limited resistance
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Antibiotics that target multiple cellular functions are anticipated to be less prone to bacterial resistance. Here we hypothesize that while dual targeting is crucial, it is not sufficient in preventing resistance. Only those antibiotics that simultaneously target membrane integrity and block another cellular pathway display reduced resistance deve...
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Full title
Exploring the principles behind antibiotics with limited resistance
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TN_cdi_doaj_primary_oai_doaj_org_article_64049a82bac7484096090352369a474e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_64049a82bac7484096090352369a474e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56934-3