Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinkin...
Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry
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Switzerland: MDPI AG
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English
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Publisher
Switzerland: MDPI AG
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Aiming to elucidate the system-wide effects of the alcohol-induced increase in the content of cytochrome P450 2E1 (CYP2E1) on drug metabolism, we explored the array of its protein-protein interactions (interactome) in human liver microsomes (HLM) with chemical crosslinking mass spectrometry (CXMS). Our strategy employs membrane incorporation of pur...
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Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry
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TN_cdi_doaj_primary_oai_doaj_org_article_6444d483dcc44f8dbd13dcbf1a4ad328
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6444d483dcc44f8dbd13dcbf1a4ad328
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom12020185
