Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin...
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling
About this item
Full title
Author / Creator
Kwon, Jeonghyeon , Kawase, Haruya , Mattonet, Kenny , Guenther, Stefan , Hahnefeld, Lisa , Shamsara, Jamal , Heering, Jan , Kurz, Michael , Kirchhofer, Sina , Krasel, Cornelius , Ulrich, Michaela , Persechino, Margherita , Murthy, Sripriya , Orlandi, Cesare , Sadik, Christian D. , Geisslinger, Gerd , Bünemann, Moritz , Kolb, Peter , Offermanns, Stefan and Wettschureck, Nina
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Macrophages express numerous G protein-coupled receptors (GPCRs) that regulate adhesion, migration, and activation, but the function of orphan receptor GPRC5B in macrophages is unknown. Both resident peritoneal and bone marrow-derived macrophages from myeloid-specific GPRC5B-deficient mice show increased migration and phagocytosis, resulting in imp...
Alternative Titles
Full title
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling
Authors, Artists and Contributors
Author / Creator
Kawase, Haruya
Mattonet, Kenny
Guenther, Stefan
Hahnefeld, Lisa
Shamsara, Jamal
Heering, Jan
Kurz, Michael
Kirchhofer, Sina
Krasel, Cornelius
Ulrich, Michaela
Persechino, Margherita
Murthy, Sripriya
Orlandi, Cesare
Sadik, Christian D.
Geisslinger, Gerd
Bünemann, Moritz
Kolb, Peter
Offermanns, Stefan
Wettschureck, Nina
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_64689d6e86354a78ab13b36978b12d29
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_64689d6e86354a78ab13b36978b12d29
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56713-0
