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Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota

Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_650da944d3904ca0b9d84f077e204850

Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota

About this item

Full title

Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-05, Vol.8 (1), p.6854-9, Article 6854

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Human microbiota-associated (HMA) mice are an important model to study the relationship between liver diseases and intestinal microbiota. We describe a new method to humanize conventional mice based on bowel cleansing with polyethylene glycol followed by fecal microbiota transplantation (FMT) from a human donor. Four successive bowel cleansings wer...

Alternative Titles

Full title

Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_650da944d3904ca0b9d84f077e204850

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_650da944d3904ca0b9d84f077e204850

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-25300-3

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