Efficient production of guanosine in Escherichia coli by combinatorial metabolic engineering
Efficient production of guanosine in Escherichia coli by combinatorial metabolic engineering
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Author / Creator
Zhang, Kun , Qin, Mengxing , Hou, Yu , Zhang, Wenwen , Wang, Zhenyu and Wang, Hailei
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Guanosine is a purine nucleoside that is widely used as a raw material for food additives and pharmaceutical products. Microbial fermentation is the main production method of guanosine. However, the guanosine-producing strains possess multiple metabolic pathway interactions and complex regulatory mechanisms. The lack of strains with efficiently pro...
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Full title
Efficient production of guanosine in Escherichia coli by combinatorial metabolic engineering
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TN_cdi_doaj_primary_oai_doaj_org_article_6515bc82d3634404abd1f111179d797a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6515bc82d3634404abd1f111179d797a
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ISSN
1475-2859
E-ISSN
1475-2859
DOI
10.1186/s12934-024-02452-8