Combined cART including Tenofovir Disoproxil, Emtricitabine, and Dolutegravir has potent therapeutic...
Combined cART including Tenofovir Disoproxil, Emtricitabine, and Dolutegravir has potent therapeutic effects in HIV-1 infected humanized mice
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Author / Creator
Weichseldorfer, Matthew , Affram, Yvonne , Heredia, Alonso , Rikhtegaran-Tehrani, Zahra , Sajadi, Mohammad M. , Williams, Sumiko P. , Tagaya, Yutaka , Benedetti, Francesca , Ramadhani, Habib O. , Denaro, Frank , Munawwar, Arshi , Bryant, Joseph , Zella, Davide , Reitz, Marvin , Romerio, Fabio and Latinovic, Olga S.
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
HIV-1 reservoirs persist in the presence of combined antiretroviral therapy (cART). However, cART has transformed HIV-1 infection into a chronic disease marked by control of HIV-1 viral load and mortality reduction. Major challenges remain, including viral resistance upon termination of cART and persistence and identification of tissue distribution...
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Full title
Combined cART including Tenofovir Disoproxil, Emtricitabine, and Dolutegravir has potent therapeutic effects in HIV-1 infected humanized mice
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TN_cdi_doaj_primary_oai_doaj_org_article_6527c26b880c42f399bb579aa07db0c0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6527c26b880c42f399bb579aa07db0c0
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-021-03120-w
