Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas
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Author / Creator
Aslan, Katrin , Turco, Verena , Blobner, Jens , Sonner, Jana K. , Liuzzi, Anna Rita , Núñez, Nicolás Gonzalo , De Feo, Donatella , Kickingereder, Philipp , Fischer, Manuel , Green, Ed , Sadik, Ahmed , Friedrich, Mirco , Sanghvi, Khwab , Kilian, Michael , Cichon, Frederik , Wolf, Lara , Jähne, Kristine , von Landenberg, Anna , Bunse, Lukas , Sahm, Felix , Schrimpf, Daniel , Meyer, Jochen , Alexander, Allen , Brugnara, Gianluca , Röth, Ralph , Pfleiderer, Kira , Niesler, Beate , von Deimling, Andreas , Opitz, Christiane , Breckwoldt, Michael O. , Heiland, Sabine , Bendszus, Martin , Wick, Wolfgang , Becher, Burkhard and Platten, Michael
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Intrinsic malignant brain tumors, such as glioblastomas are frequently resistant to immune checkpoint blockade (ICB) with few hypermutated glioblastomas showing response. Modeling patient-individual resistance is challenging due to the lack of predictive biomarkers and limited accessibility of tissue for serial biopsies. Here, we investigate resist...
Alternative Titles
Full title
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas
Authors, Artists and Contributors
Author / Creator
Turco, Verena
Blobner, Jens
Sonner, Jana K.
Liuzzi, Anna Rita
Núñez, Nicolás Gonzalo
De Feo, Donatella
Kickingereder, Philipp
Fischer, Manuel
Green, Ed
Sadik, Ahmed
Friedrich, Mirco
Sanghvi, Khwab
Kilian, Michael
Cichon, Frederik
Wolf, Lara
Jähne, Kristine
von Landenberg, Anna
Bunse, Lukas
Sahm, Felix
Schrimpf, Daniel
Meyer, Jochen
Alexander, Allen
Brugnara, Gianluca
Röth, Ralph
Pfleiderer, Kira
Niesler, Beate
von Deimling, Andreas
Opitz, Christiane
Breckwoldt, Michael O.
Heiland, Sabine
Bendszus, Martin
Wick, Wolfgang
Becher, Burkhard
Platten, Michael
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_65441a7f16a24904a9e706ac1ace56b2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_65441a7f16a24904a9e706ac1ace56b2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-14642-0
