Splicing accuracy varies across human introns, tissues, age and disease
Splicing accuracy varies across human introns, tissues, age and disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Alternative splicing impacts most multi-exonic human genes. Inaccuracies during this process may have an important role in ageing and disease. Here, we investigate splicing accuracy using RNA-sequencing data from >14k control samples and 40 human body sites, focusing on split reads partially mapping to known transcripts in annotation. We show that...
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Splicing accuracy varies across human introns, tissues, age and disease
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TN_cdi_doaj_primary_oai_doaj_org_article_6555f7c62a4047a48b17a88a6825e58e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6555f7c62a4047a48b17a88a6825e58e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-55607-x
