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β2-Chimaerin Deficiency Favors Polyp Growth in the Colon of ApcMin/+ Mice

β2-Chimaerin Deficiency Favors Polyp Growth in the Colon of ApcMin/+ Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_657cbffe515b4d51b53b64582fa2d0c0

β2-Chimaerin Deficiency Favors Polyp Growth in the Colon of ApcMin/+ Mice

About this item

Full title

β2-Chimaerin Deficiency Favors Polyp Growth in the Colon of ApcMin/+ Mice

Publisher

Basel: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2025-02, Vol.30 (4), p.824

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

A Rho-GTPases are pivotal regulators of key cellular processes implicated in colorectal cancer (CRC) progression, yet the roles of their regulatory proteins, particularly GTPase-activating proteins (GAPs), remain poorly understood. This study focuses on β2-chimaerin, a Rac1-specific GAP, in Apc-driven tumorigenesis using the ApcMin/+ mouse model. W...

Alternative Titles

Full title

β2-Chimaerin Deficiency Favors Polyp Growth in the Colon of ApcMin/+ Mice

Authors, Artists and Contributors

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Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_657cbffe515b4d51b53b64582fa2d0c0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_657cbffe515b4d51b53b64582fa2d0c0

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules30040824

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