Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex w...
Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum
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Publisher
San Francisco, CA USA: Public Library of Science
Journal title
Language
English
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Publisher
San Francisco, CA USA: Public Library of Science
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Scope and Contents
Contents
The Lamc2.sup.jeb junctional epidermolysis bullosa (EB) mouse model has been used to demonstrate that significant genetic modification of EB symptoms is possible, identifying as modifiers Col17a1 and six other quantitative trait loci, several with strong candidate genes including dystonin (Dst/Bpag1). Here, CRISPR/Cas9 was used to alter exon 23 in...
Alternative Titles
Full title
Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum
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TN_cdi_doaj_primary_oai_doaj_org_article_658a1999797249b9a32a5a0a6180cfda
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_658a1999797249b9a32a5a0a6180cfda
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0293218
