Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential a...
Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential and a population with transcriptional immune response
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Author / Creator
Fritze, Jonas , Lang, Stefan , Sommarin, Mikael , Soneji, Shamit , Ahlenius, Henrik , Division of Molecular Hematology (DMH) , Strategiska forskningsområden (SFO) , Department of Experimental Medical Science , Department of Laboratory Medicine , Strategic research areas (SRA) , Neurology, Lund , Department of Clinical Sciences, Lund , Avdelningen för molekylär hematologi , Lund University , Institutionen för laboratoriemedicin , Profile areas and other strong research environments , Stem Cells and Leukemia , Faculty of Medicine , Medicinska fakulteten , StemTherapy: National Initiative on Stem Cells for Regenerative Therapy , Institutionen för kliniska vetenskaper, Lund , Lunds universitet , Stamceller, åldrande och neurodegeneration , Sektion IV , Profilområden och andra starka forskningsmiljöer , Section IV , Neurologi, Lund , MultiPark: Multidisciplinary research focused on Parkinson´s disease , Stem Cells, Aging and Neurodegeneration , Institutionen för experimentell medicinsk vetenskap and eSSENCE: The e-Science Collaboration
Publisher
Switzerland: Frontiers Media S.A
Journal title
Language
English
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Publication information
Publisher
Switzerland: Frontiers Media S.A
Subjects
More information
Scope and Contents
Contents
In the adult murine brain, neural stem cells (NSCs) can be found in two main niches: the dentate gyrus (DG) and the subventricular zone (SVZ). In the DG, NSCs produce intermediate progenitors (IPs) that differentiate into excitatory neurons, while progenitors in the SVZ migrate to the olfactory bulb (OB), where they mainly differentiate into inhibi...
Alternative Titles
Full title
Single-cell RNA sequencing of aging neural progenitors reveals loss of excitatory neuron potential and a population with transcriptional immune response
Authors, Artists and Contributors
Author / Creator
Lang, Stefan
Sommarin, Mikael
Soneji, Shamit
Ahlenius, Henrik
Division of Molecular Hematology (DMH)
Strategiska forskningsområden (SFO)
Department of Experimental Medical Science
Department of Laboratory Medicine
Strategic research areas (SRA)
Neurology, Lund
Department of Clinical Sciences, Lund
Avdelningen för molekylär hematologi
Lund University
Institutionen för laboratoriemedicin
Profile areas and other strong research environments
Stem Cells and Leukemia
Faculty of Medicine
Medicinska fakulteten
StemTherapy: National Initiative on Stem Cells for Regenerative Therapy
Institutionen för kliniska vetenskaper, Lund
Lunds universitet
Stamceller, åldrande och neurodegeneration
Sektion IV
Profilområden och andra starka forskningsmiljöer
Section IV
Neurologi, Lund
MultiPark: Multidisciplinary research focused on Parkinson´s disease
Stem Cells, Aging and Neurodegeneration
Institutionen för experimentell medicinsk vetenskap
eSSENCE: The e-Science Collaboration
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_658f183bf70346a79fc7199274d178db
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_658f183bf70346a79fc7199274d178db
Other Identifiers
ISSN
1662-453X,1662-4548
E-ISSN
1662-453X
DOI
10.3389/fnins.2024.1400963
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