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Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis o...

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_65d6714ebc4c4cc289e1fce88f12a77f

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

About this item

Full title

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

Publisher

England: BioMed Central Ltd

Journal title

Critical care (London, England), 2023-03, Vol.27 (1), p.126-9, Article 126

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Two acute respiratory distress syndrome (ARDS) trials showed no benefit for statin therapy, though secondary analyses suggest inflammatory subphenotypes may have a differential response to simvastatin. Statin medications decrease cholesterol levels, and low cholesterol has been associated with increased mortality in critical illness. We hypothesize...

Alternative Titles

Full title

Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_65d6714ebc4c4cc289e1fce88f12a77f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_65d6714ebc4c4cc289e1fce88f12a77f

Other Identifiers

ISSN

1364-8535,1466-609X

E-ISSN

1466-609X,1364-8535,1366-609X

DOI

10.1186/s13054-023-04387-9

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