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Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_65e9ecff6a5e4bf9bde0b3289d249518

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

About this item

Full title

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-09, Vol.9 (1), p.3801-9, Article 3801

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Artemisinin and its derivatives (collectively referred to as ARTs) rapidly reduce the parasite burden in
Plasmodium falciparum
infections, and antimalarial control is highly dependent on ART combination therapies (ACTs). Decreased sensitivity to ARTs is emerging, making it critically important to understand the mechanism of action of ARTs. He...

Alternative Titles

Full title

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_65e9ecff6a5e4bf9bde0b3289d249518

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_65e9ecff6a5e4bf9bde0b3289d249518

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-06221-1

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