Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Artemisinin and its derivatives (collectively referred to as ARTs) rapidly reduce the parasite burden in
Plasmodium falciparum
infections, and antimalarial control is highly dependent on ART combination therapies (ACTs). Decreased sensitivity to ARTs is emerging, making it critically important to understand the mechanism of action of ARTs. He...
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Full title
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
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TN_cdi_doaj_primary_oai_doaj_org_article_65e9ecff6a5e4bf9bde0b3289d249518
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_65e9ecff6a5e4bf9bde0b3289d249518
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06221-1