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Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine...

Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6614f4cf216b4fbd8648d890b4621aae

Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells

About this item

Full title

Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2015-06, Vol.4, p.e06990-e06990

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Type 1 diabetes (T1D) is an autoimmune disease caused by loss of pancreatic β cells via apoptosis while neighboring α cells are preserved. Viral infections by coxsackieviruses (CVB) may contribute to trigger autoimmunity in T1D. Cellular permissiveness to viral infection is modulated by innate antiviral responses, which vary among different cell ty...

Alternative Titles

Full title

Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6614f4cf216b4fbd8648d890b4621aae

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6614f4cf216b4fbd8648d890b4621aae

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.06990

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