Evaluation of a simplified radiolabeling method for a PARP inhibitor in an animal model of breast ca...
Evaluation of a simplified radiolabeling method for a PARP inhibitor in an animal model of breast cancer
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Background
Several poly (adenosine diphosphate–ribose) polymerase (PARP) inhibitors were recently approved by the US Food and Drug Administration for use in cancer treatment. To facilitate the discovery of novel PARP-targeting ligands, a radioiodinated ligand, I-125-KX1, was developed and validated for its specificity to PARP-1; however, its pre...
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Full title
Evaluation of a simplified radiolabeling method for a PARP inhibitor in an animal model of breast cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_663174ecedf04e0d8c5d530bd3168acd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_663174ecedf04e0d8c5d530bd3168acd
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ISSN
2191-219X
E-ISSN
2191-219X
DOI
10.1186/s13550-025-01236-4
