Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome
Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Angelman syndrome (AS) is a neurogenetic disorder characterized by intellectual disability and atypical behaviors. AS results from loss of expression of the E3 ubiquitin-protein ligase UBE3A from the maternal allele in neurons. Individuals with AS display impaired coordination, poor balance, and gait ataxia. PIEZO2 is a mechanosensitive ion channel...
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Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome
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TN_cdi_doaj_primary_oai_doaj_org_article_664f09f3735d4266a19b95c85b38e994
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_664f09f3735d4266a19b95c85b38e994
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-36818-0
