Synthesis of 1,2,4-Oxadiazin-5(6H)-One Derivatives and Their Biological Investigation as Monoamine O...
Synthesis of 1,2,4-Oxadiazin-5(6H)-One Derivatives and Their Biological Investigation as Monoamine Oxidase Inhibitors
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Author / Creator
Presnukhina, Sofia I. , Kotlyarova, Valentina D. , Shetnev, Anton A. , Baykov, Sergey V. , Turmanov, Rakhymzhan , Appazov, Nurbol , Zhapparbergenov, Rakhmetulla , Zhussupova, Leilya , Togyzbayeva, Nurila , Cloete, Stephanus J. , Korsakov, Mikhail K. , Boyarskiy, Vadim P. , Petzer, Anél and Petzer, Jacobus P.
Publisher
Switzerland: MDPI AG
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English
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Publisher
Switzerland: MDPI AG
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Contents
Monoamine oxidase (MAO) plays a key role in the pathogenesis of central nervous system disorders, and MAO inhibitors have been used in the treatment of depression and Parkinson’s disease. In the search for new classes of MAO inhibitors, the present study investigated a series of 1,2,4-oxadiazin-5(6H)-one derivatives. This study provides the first o...
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Full title
Synthesis of 1,2,4-Oxadiazin-5(6H)-One Derivatives and Their Biological Investigation as Monoamine Oxidase Inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_666d1696e3a345529b3f8441fd9f2dec
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_666d1696e3a345529b3f8441fd9f2dec
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules29235550
