An oncogenic splice variant of PDGFRα in adult glioblastoma as a therapeutic target for selective CD...
An oncogenic splice variant of PDGFRα in adult glioblastoma as a therapeutic target for selective CDK4/6 inhibitors
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Understanding human genome alterations is necessary to optimize genome-based cancer therapeutics. However, some newly discovered mutations remain as variants of unknown significance (VUS). Here, the mutation c.1403A > G in exon 10 of the platelet-derived growth factor receptor-alpha (
PDGFRA
) gene, a VUS found in adult glioblastoma multiform...
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Full title
An oncogenic splice variant of PDGFRα in adult glioblastoma as a therapeutic target for selective CDK4/6 inhibitors
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TN_cdi_doaj_primary_oai_doaj_org_article_6674d42c09f94f549df969b2710ed483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6674d42c09f94f549df969b2710ed483
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-05391-9
