Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure...
Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Nebulin is a critical thin filament-binding protein that spans from the Z-disk of the skeletal muscle sarcomere to near the pointed end of the thin filament. Its massive size and actin-binding property allows it to provide the thin filaments with structural and regulatory support. When this protein is lost, nemaline myopathy occurs. Nemaline myopat...
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Full title
Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function
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TN_cdi_doaj_primary_oai_doaj_org_article_667904beb85d45bf8b0810fff5560535
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_667904beb85d45bf8b0810fff5560535
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ISSN
2044-5040
E-ISSN
2044-5040
DOI
10.1186/s13395-019-0219-9
