Zn2+-dependent DNAzymes that cleave all combinations of ribonucleotides
Zn2+-dependent DNAzymes that cleave all combinations of ribonucleotides
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Although several DNAzymes are known, their utility is limited by a narrow range of substrate specificity. Here, we report the isolation of two zinc-dependent DNAzymes, ZincDz1 and ZincDz2, which exhibit compact catalytic core sequences with highly versatile hydrolysis activity. They were selected through in vitro selection followed by deep sequenci...
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Full title
Zn2+-dependent DNAzymes that cleave all combinations of ribonucleotides
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TN_cdi_doaj_primary_oai_doaj_org_article_667af51242b84672bb30a21379eb5f19
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_667af51242b84672bb30a21379eb5f19
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-01738-6
