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Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tR...

Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tR...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_667bbdd85bcf4f5d859b6bc8c2d4b1e1

Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tRNA set

About this item

Full title

Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tRNA set

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-05, Vol.15 (1), p.4143-4143, Article 4143

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The Ser/Leu-swapped genetic code can act as a genetic firewall, mitigating biohazard risks arising from horizontal gene transfer in genetically modified organisms. Our prior work demonstrated the orthogonality of this swapped code to the standard genetic code using a cell-free translation system comprised of 21 in vitro transcribed tRNAs. In this s...

Alternative Titles

Full title

Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tRNA set

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_667bbdd85bcf4f5d859b6bc8c2d4b1e1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_667bbdd85bcf4f5d859b6bc8c2d4b1e1

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-48056-z

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