Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tR...
Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tRNA set
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The Ser/Leu-swapped genetic code can act as a genetic firewall, mitigating biohazard risks arising from horizontal gene transfer in genetically modified organisms. Our prior work demonstrated the orthogonality of this swapped code to the standard genetic code using a cell-free translation system comprised of 21 in vitro transcribed tRNAs. In this s...
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Ser/Leu-swapped cell-free translation system constructed with natural/in vitro transcribed-hybrid tRNA set
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TN_cdi_doaj_primary_oai_doaj_org_article_667bbdd85bcf4f5d859b6bc8c2d4b1e1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_667bbdd85bcf4f5d859b6bc8c2d4b1e1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-48056-z