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Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6695fdf7fa9f4cceb2741307353a71cf

Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

About this item

Full title

Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2018-10, Vol.7

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

In most well-studied rod-shaped bacteria, peptidoglycan is primarily crosslinked by penicillin-binding proteins (PBPs). However, in mycobacteria, crosslinks formed by L,D-transpeptidases (LDTs) are highly abundant. To elucidate the role of these unusual crosslinks, we characterized Mycobacterium smegmatis cells lacking all LDTs. We find that crossl...

Alternative Titles

Full title

Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6695fdf7fa9f4cceb2741307353a71cf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6695fdf7fa9f4cceb2741307353a71cf

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.37516

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