ADDME – Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective
ADDME – Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The advent of early absorption, distribution, metabolism, excretion, and toxicity (ADMET) screening has increased the attrition rate of weak drug candidates early in the drug-discovery process, and decreased the proportion of compounds failing in clinical trials for ADMET reasons. This paper reviews the history of ADMET screening and its place in p...
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Full title
ADDME – Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective
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TN_cdi_doaj_primary_oai_doaj_org_article_66ba20c184504af3a920cf4d943d1840
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_66ba20c184504af3a920cf4d943d1840
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ISSN
1471-2377
E-ISSN
1471-2377
DOI
10.1186/1471-2377-9-S1-S1
