Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome
Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome
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Author / Creator
Sun, Xinlei , Qu, Shuang , Zhou, Fenglian , Shi, Fujie , Wu, Yunfei , Gu, Lin , Liu, Minghui , Bian, Zhen , Shi, Lei , Liu, Zhihong , Liu, Yuan and Zen, Ke
Publisher
England: BioMed Central
Journal title
Language
English
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Publisher
England: BioMed Central
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Scope and Contents
Contents
Shiga toxin (Stx)-induced hemolytic uremic syndrome (HUS) poses a life-threatening complication for which a definitive treatment remains elusive. To exert its cytotoxic effect on renal cells, Stx must be delivered from the infected intestines to the kidney. However, the mechanism underlying Stx delivery remains unclear. Here we pinpoint monocytes a...
Alternative Titles
Full title
Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_66fb23e3744a4992a460983375532b55
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_66fb23e3744a4992a460983375532b55
Other Identifiers
ISSN
1689-1392,1425-8153
E-ISSN
1689-1392
DOI
10.1186/s11658-025-00689-8
