Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase
Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase
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Author / Creator
Xu, Jian , Fan, Jiajie , Lou, Yujiao , Xu, Weihua , Wang, Zhiguo , Li, Danyang , Zhou, Haonan , Lin, Xianfu and Wu, Qi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Despite the well-established chemical processes for C-D bond formation, the toolbox of enzymatic methodologies for deuterium incorporation has remained underdeveloped. Here we describe a photodecarboxylase from
Chlorella variabilis
NC64A (
Cv
FAP)-catalyzed approach for the decarboxylative deuteration of various carboxylic acids by empl...
Alternative Titles
Full title
Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_671c1dc0e8124a00b5cc1aca053d9f9f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_671c1dc0e8124a00b5cc1aca053d9f9f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24259-6
