Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to...
Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma
About this item
Full title
Author / Creator
Diazzi, Serena , Baeri, Alberto , Fassy, Julien , Lecacheur, Margaux , Marin‐Bejar, Oskar , Girard, Christophe A , Lefevre, Lauren , Lacoux, Caroline , Irondelle, Marie , Mounier, Carine , Truchi, Marin , Couralet, Marie , Ohanna, Mickael , Carminati, Alexandrine , Berestjuk, Ilona , Larbret, Frederic , Gilot, David , Vassaux, Georges , Marine, Jean‐Christophe , Deckert, Marcel , Mari, Bernard and Tartare‐Deckert, Sophie
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Lineage dedifferentiation toward a mesenchymal‐like state displaying myofibroblast and fibrotic features is a common mechanism of adaptive and acquired resistance to targeted therapy in melanoma. Here, we show that the anti‐fibrotic drug nintedanib is active to normalize the fibrous ECM network, enhance the efficacy of MAPK‐targeted therapy, and de...
Alternative Titles
Full title
Blockade of the pro‐fibrotic reaction mediated by the miR‐143/‐145 cluster enhances the responses to targeted therapy in melanoma
Authors, Artists and Contributors
Author / Creator
Baeri, Alberto
Fassy, Julien
Lecacheur, Margaux
Marin‐Bejar, Oskar
Girard, Christophe A
Lefevre, Lauren
Lacoux, Caroline
Irondelle, Marie
Mounier, Carine
Truchi, Marin
Couralet, Marie
Ohanna, Mickael
Carminati, Alexandrine
Berestjuk, Ilona
Larbret, Frederic
Gilot, David
Vassaux, Georges
Marine, Jean‐Christophe
Deckert, Marcel
Mari, Bernard
Tartare‐Deckert, Sophie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_671e1303a548439c811055b9bfe4b17f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_671e1303a548439c811055b9bfe4b17f
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.202115295
