Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutati...
Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Mutations in isocitrate dehydrogenase 1 (
IDH1
) and
IDH2
are oncogenic drivers to a variable extent in several tumors, including gliomas, acute myeloid leukemia (AML), cholangiocarcinoma, melanoma, and thyroid carcinoma. The pathobiological effects of these mutations vary considerably, impeding the identification of common expression p...
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Full title
Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models
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TN_cdi_doaj_primary_oai_doaj_org_article_67296b160a7742238af9ec1062355f36
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67296b160a7742238af9ec1062355f36
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-04214-7
