Simulation of the In Vivo Fate of Polymeric Nanoparticles Traced by Environment-Responsive Near-Infr...
Simulation of the In Vivo Fate of Polymeric Nanoparticles Traced by Environment-Responsive Near-Infrared Dye: A Physiologically Based Pharmacokinetic Modelling Approach
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Author / Creator
Li, Lei , He, Haisheng , Jiang, Sifang , Qi, Jianping , Lu, Yi , Ding, Ning , Lin, Hai-Shu , Wu, Wei and Xiang, Xiaoqiang
Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The application of physiologically based pharmacokinetic models to nanoparticles is still very restricted and challenging, owing to the complicated in vivo transport mechanisms involving nanoparticles, including phagocytosis, enhanced permeability and retention effects, cellular recognition, and internalisation, enzymatic degradation, lymphatic tra...
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Full title
Simulation of the In Vivo Fate of Polymeric Nanoparticles Traced by Environment-Responsive Near-Infrared Dye: A Physiologically Based Pharmacokinetic Modelling Approach
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TN_cdi_doaj_primary_oai_doaj_org_article_6777dfb550094769ba396db4f9e85e66
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6777dfb550094769ba396db4f9e85e66
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26051271