Log in to save to my catalogue

Astroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model

Astroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_677e0f459eba49d6aa9029b65a57d82b

Astroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model

About this item

Full title

Astroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-05, Vol.14 (1), p.10877-23, Article 10877

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In chronic stages of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalitis (EAE), connexin (Cx)43 gap junction channel proteins are overexpressed because of astrogliosis. To elucidate the role of increased Cx43, the central nervous system (CNS)-permeable Cx blocker INI-0602 was therapeutically administered. C57BL6 mice...

Alternative Titles

Full title

Astroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_677e0f459eba49d6aa9029b65a57d82b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_677e0f459eba49d6aa9029b65a57d82b

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-61508-2

How to access this item