Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular...
Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma
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Author / Creator
Liao, Junbin , Jin, Huilin , Li, Shaoqiang , Xu, Lixia , Peng, Zhenwei , Wei, Guangyan , Long, Jianting , Guo, Yu , Kuang, Ming , Zhou, Qi and Peng, Sui
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Limited effective intervention for advanced hepatocellular carcinoma (HCC) is available. This study aimed to investigate the potential clinical utility of apatinib, a highly selective inhibitor of the vascular endothelial growth factor receptor-2 (VEGFR2) tyrosine kinase, as a radiosensitizer in the treatment of HCC.
Four human HCC cell lines SM...
Alternative Titles
Full title
Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_67bd6ff4e5d942b0a741ce9b2e90b45d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67bd6ff4e5d942b0a741ce9b2e90b45d
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-019-1419-1