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Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular...

Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67bd6ff4e5d942b0a741ce9b2e90b45d

Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma

About this item

Full title

Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma

Publisher

England: BioMed Central Ltd

Journal title

Journal of experimental & clinical cancer research, 2019-11, Vol.38 (1), p.454-454, Article 454

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Limited effective intervention for advanced hepatocellular carcinoma (HCC) is available. This study aimed to investigate the potential clinical utility of apatinib, a highly selective inhibitor of the vascular endothelial growth factor receptor-2 (VEGFR2) tyrosine kinase, as a radiosensitizer in the treatment of HCC.
Four human HCC cell lines SM...

Alternative Titles

Full title

Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_67bd6ff4e5d942b0a741ce9b2e90b45d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67bd6ff4e5d942b0a741ce9b2e90b45d

Other Identifiers

ISSN

1756-9966,0392-9078

E-ISSN

1756-9966

DOI

10.1186/s13046-019-1419-1

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