Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance
About this item
Full title
Author / Creator
Pietilä, Elina A. , Gonzalez-Molina, Jordi , Moyano-Galceran, Lidia , Jamalzadeh, Sanaz , Zhang, Kaiyang , Lehtinen, Laura , Turunen, S. Pauliina , Martins, Tomás A. , Gultekin, Okan , Lamminen, Tarja , Kaipio, Katja , Joneborg, Ulrika , Hynninen, Johanna , Hietanen, Sakari , Grénman, Seija , Lehtonen, Rainer , Hautaniemi, Sampsa , Carpén, Olli , Carlson, Joseph W. and Lehti, Kaisa
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Due to its dynamic nature, the evolution of cancer cell-extracellular matrix (ECM) crosstalk, critically affecting metastasis and treatment resistance, remains elusive. Our results show that platinum-chemotherapy itself enhances resistance by progressively changing the cancer cell-intrinsic adhesion signaling and cell-surrounding ECM. Examining ova...
Alternative Titles
Full title
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance
Authors, Artists and Contributors
Author / Creator
Gonzalez-Molina, Jordi
Moyano-Galceran, Lidia
Jamalzadeh, Sanaz
Zhang, Kaiyang
Lehtinen, Laura
Turunen, S. Pauliina
Martins, Tomás A.
Gultekin, Okan
Lamminen, Tarja
Kaipio, Katja
Joneborg, Ulrika
Hynninen, Johanna
Hietanen, Sakari
Grénman, Seija
Lehtonen, Rainer
Hautaniemi, Sampsa
Carpén, Olli
Carlson, Joseph W.
Lehti, Kaisa
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_67c04582b2c44334b40a53907f9099c4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67c04582b2c44334b40a53907f9099c4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24009-8
