Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dime...
Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Cancer-associated fibroblasts (CAFs) are considered to play a fundamental role in pancreatic ductal adenocarcinoma (PDAC) progression and chemoresistance. Patient-derived organoids have demonstrated great potential as tumor avatars for drug response prediction in PDAC, yet they disregard the influence of stromal components on chemosensitivity.
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Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system
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TN_cdi_doaj_primary_oai_doaj_org_article_67e84cf093684d099e7a2f8d345931a2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67e84cf093684d099e7a2f8d345931a2
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-022-02519-7
