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Trazodone effects on developing brain

Trazodone effects on developing brain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67ed1de6baf7469e8270dfd73a93f59e

Trazodone effects on developing brain

About this item

Full title

Trazodone effects on developing brain

Publisher

London: Nature Publishing Group UK

Journal title

Translational psychiatry, 2021-02, Vol.11 (1), p.85-9, Article 85

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Trazodone (TRZ) is a commonly prescribed antidepressant with significant off-label use for insomnia. A recent drug screening revealed that TRZ interferes with sterol biosynthesis, causing elevated levels of sterol precursor 7-dehydrocholesterol (7-DHC). Recognizing the well-documented, disruptive effect of 7-DHC on brain development, we designed a...

Alternative Titles

Full title

Trazodone effects on developing brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_67ed1de6baf7469e8270dfd73a93f59e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67ed1de6baf7469e8270dfd73a93f59e

Other Identifiers

ISSN

2158-3188

E-ISSN

2158-3188

DOI

10.1038/s41398-021-01217-w

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