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A flexible framework for minimal biomarker signature discovery from clinical omics studies without l...

A flexible framework for minimal biomarker signature discovery from clinical omics studies without l...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67f228224b08449bade2b3d7f2eefd0d

A flexible framework for minimal biomarker signature discovery from clinical omics studies without library size normalisation

About this item

Full title

A flexible framework for minimal biomarker signature discovery from clinical omics studies without library size normalisation

Publisher

United States: Public Library of Science

Journal title

PLOS digital health, 2025-03, Vol.4 (3), p.e0000780

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Application of transcriptomics, proteomics and metabolomics technologies to clinical cohorts has uncovered a variety of signatures for predicting disease. Many of these signatures require the full ‘omics data for evaluation on unseen samples, either explicitly or implicitly through library size normalisation. Translation to low-cost point-of-care t...

Alternative Titles

Full title

A flexible framework for minimal biomarker signature discovery from clinical omics studies without library size normalisation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_67f228224b08449bade2b3d7f2eefd0d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67f228224b08449bade2b3d7f2eefd0d

Other Identifiers

ISSN

2767-3170

E-ISSN

2767-3170

DOI

10.1371/journal.pdig.0000780

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