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In vitro activity of rifampicin, rifapentine and rifabutin in combination with their 25-deacetyl-met...

In vitro activity of rifampicin, rifapentine and rifabutin in combination with their 25-deacetyl-met...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67ff35ba899a4c76991842285d90dc08

In vitro activity of rifampicin, rifapentine and rifabutin in combination with their 25-deacetyl-metabolites against various Mycobacterium tuberculosis lineages

About this item

Full title

In vitro activity of rifampicin, rifapentine and rifabutin in combination with their 25-deacetyl-metabolites against various Mycobacterium tuberculosis lineages

Publisher

England: BioMed Central Ltd

Journal title

Annals of clinical microbiology and antimicrobials, 2025-02, Vol.24 (1), p.16-6, Article 16

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Rifamycin agents (rifampicin (RIF), rifapentine (RFP), rifabutin (RFB)) are the cornerstone of tuberculosis (TB) therapy. Rifamycins are metabolized into 25-deacetyl-metabolites, which have been described has active and may contribute to in vivo drug effect. However, little is known about the combined effect of rifamycins and their metabolites acro...

Alternative Titles

Full title

In vitro activity of rifampicin, rifapentine and rifabutin in combination with their 25-deacetyl-metabolites against various Mycobacterium tuberculosis lineages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_67ff35ba899a4c76991842285d90dc08

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_67ff35ba899a4c76991842285d90dc08

Other Identifiers

ISSN

1476-0711

E-ISSN

1476-0711

DOI

10.1186/s12941-025-00784-w

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