Intravenous immunoglobulin and rituximab versus placebo treatment of antibody-associated psychosis:...
Intravenous immunoglobulin and rituximab versus placebo treatment of antibody-associated psychosis: study protocol of a randomised phase IIa double-blinded placebo-controlled trial (SINAPPS2)
About this item
Full title
Author / Creator
Lennox, Belinda , Yeeles, Ksenija , Jones, Peter B. , Zandi, Michael , Joyce, Eileen , Yu, Ly-Mee , Tomei, Giuliano , Pollard, Rebecca , Vincent, Sally-Anne , Shimazaki, Mio , Cairns, Iona , Dowling, Francis , Kabir, Thomas , Barnes, Thomas R. E. , Lingford Hughes, Anne , Hosseini, Akram A. , Harrower, Timothy , Buckley, Camilla and Coles, Alasdair
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Evidence is conflicting about a causal role of inflammation in psychosis and, specifically, regarding antibodies binding to neuronal membrane targets, especially N-methyl-D-aspartate receptors. NMDAR, LGI1 and GABA-A antibodies were found more prevalent in people with psychosis than in healthy controls. We aim to test whether these antibodies are p...
Alternative Titles
Full title
Intravenous immunoglobulin and rituximab versus placebo treatment of antibody-associated psychosis: study protocol of a randomised phase IIa double-blinded placebo-controlled trial (SINAPPS2)
Authors, Artists and Contributors
Author / Creator
Yeeles, Ksenija
Jones, Peter B.
Zandi, Michael
Joyce, Eileen
Yu, Ly-Mee
Tomei, Giuliano
Pollard, Rebecca
Vincent, Sally-Anne
Shimazaki, Mio
Cairns, Iona
Dowling, Francis
Kabir, Thomas
Barnes, Thomas R. E.
Lingford Hughes, Anne
Hosseini, Akram A.
Harrower, Timothy
Buckley, Camilla
Coles, Alasdair
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_680f20e461b947d291e244f28a825ed9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_680f20e461b947d291e244f28a825ed9
Other Identifiers
ISSN
1745-6215
E-ISSN
1745-6215
DOI
10.1186/s13063-019-3336-1