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Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen

Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_682c2f89a691488ab8985bb1b427bede

Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen

About this item

Full title

Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-02, Vol.16 (1), p.1262-16, Article 1262

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

T cell receptor-engineered T cells (TCR-T) could be advantageous in glioblastoma by allowing safe and ubiquitous targeting of the glioblastoma-derived peptidome. Protein tyrosine phosphatase receptor type Z1 (PTPRZ1), is a clinically targetable glioblastoma antigen associated with glioblastoma cell stemness. Here, we identify a therapeutic HLA-A*02...

Alternative Titles

Full title

Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_682c2f89a691488ab8985bb1b427bede

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_682c2f89a691488ab8985bb1b427bede

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-025-56547-w

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