Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen
Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen
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Author / Creator
Chih, Yu-Chan , Dietsch, Amelie C. , Koopmann, Philipp , Ma, Xiujian , Agardy, Dennis A. , Zhao, Binghao , De Roia, Alice , Kourtesakis, Alexandros , Kilian, Michael , Krämer, Christopher , Suwala, Abigail K. , Stenzinger, Miriam , Boenig, Halvard , Blum, Agnieszka , Pienkowski, Victor Murcia , Aman, Kuralay , Becker, Jonas P. , Feldmann, Henrike , Bunse, Theresa , Harbottle, Richard , Riemer, Angelika B. , Liu, Hai-Kun , Etminan, Nima , Sahm, Felix , Ratliff, Miriam , Wick, Wolfgang , Platten, Michael , Green, Edward W. and Bunse, Lukas
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
T cell receptor-engineered T cells (TCR-T) could be advantageous in glioblastoma by allowing safe and ubiquitous targeting of the glioblastoma-derived peptidome. Protein tyrosine phosphatase receptor type Z1 (PTPRZ1), is a clinically targetable glioblastoma antigen associated with glioblastoma cell stemness. Here, we identify a therapeutic HLA-A*02...
Alternative Titles
Full title
Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen
Authors, Artists and Contributors
Author / Creator
Dietsch, Amelie C.
Koopmann, Philipp
Ma, Xiujian
Agardy, Dennis A.
Zhao, Binghao
De Roia, Alice
Kourtesakis, Alexandros
Kilian, Michael
Krämer, Christopher
Suwala, Abigail K.
Stenzinger, Miriam
Boenig, Halvard
Blum, Agnieszka
Pienkowski, Victor Murcia
Aman, Kuralay
Becker, Jonas P.
Feldmann, Henrike
Bunse, Theresa
Harbottle, Richard
Riemer, Angelika B.
Liu, Hai-Kun
Etminan, Nima
Sahm, Felix
Ratliff, Miriam
Wick, Wolfgang
Platten, Michael
Green, Edward W.
Bunse, Lukas
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_682c2f89a691488ab8985bb1b427bede
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_682c2f89a691488ab8985bb1b427bede
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56547-w