Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclizat...
Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Viral replicase recruitment and long-range RNA interactions are essential for RNA virus replication, yet the mechanism of their interplay remains elusive. Flaviviruses include numerous important human pathogens, e.g., dengue virus (DENV) and Zika virus (ZIKV). Here, we revealed a highly conserved, conformation-tunable
-acting element named 5'-UA...
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Full title
Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization
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TN_cdi_doaj_primary_oai_doaj_org_article_685f7a9f995943f2a4a0aad9ef4ed5e4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_685f7a9f995943f2a4a0aad9ef4ed5e4
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.17636
