Log in to save to my catalogue

BRCA1 & BRCA2 methylation as a prognostic and predictive biomarker in cancer: Implementation in liqu...

BRCA1 & BRCA2 methylation as a prognostic and predictive biomarker in cancer: Implementation in liqu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6860685ecf794e52a09d6cf7b7bdd569

BRCA1 & BRCA2 methylation as a prognostic and predictive biomarker in cancer: Implementation in liquid biopsy in the era of precision medicine

About this item

Full title

BRCA1 & BRCA2 methylation as a prognostic and predictive biomarker in cancer: Implementation in liquid biopsy in the era of precision medicine

Publisher

Germany: BioMed Central Ltd

Journal title

Clinical epigenetics, 2024-12, Vol.16 (1), p.178-16, Article 178

Language

English

Formats

Publication information

Publisher

Germany: BioMed Central Ltd

More information

Scope and Contents

Contents

BReast CAncer gene 1 (BRCA1) and BReast CAncer gene 2 (BRCA2) encode for tumor suppressor proteins which are critical regulators of the Homologous Recombination (HR) pathway, the most precise and important DNA damage response mechanism. Dysfunctional HR proteins cannot repair double-stranded DNA breaks in mammalian cells, a situation called HR defi...

Alternative Titles

Full title

BRCA1 & BRCA2 methylation as a prognostic and predictive biomarker in cancer: Implementation in liquid biopsy in the era of precision medicine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6860685ecf794e52a09d6cf7b7bdd569

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6860685ecf794e52a09d6cf7b7bdd569

Other Identifiers

ISSN

1868-7083,1868-7075

E-ISSN

1868-7083

DOI

10.1186/s13148-024-01787-8

How to access this item