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Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_68623bc3e237447ba32f6afbac61397c

Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

About this item

Full title

Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2020-04, Vol.9

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The H2A.Z histone variant, a genome-wide hallmark of permissive chromatin, is enriched near transcription start sites in all eukaryotes. H2A.Z is deposited by the SWR1 chromatin remodeler and evicted by unclear mechanisms. We tracked H2A.Z in living yeast at single-molecule resolution, and found that H2A.Z eviction is dependent on RNA Polymerase II...

Alternative Titles

Full title

Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_68623bc3e237447ba32f6afbac61397c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_68623bc3e237447ba32f6afbac61397c

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.55667

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